We know that Travis Strikes Again: No More Heroes is a spin-off for the No More Heroes franchise, but why exactly did Suda51 go with the name he did? In an interview with Game Informer, Suda51 offers up an answer.
I wanted to give Travis a new adventure and a new experience. Up until now you know he's been fighting as an assassin, but this time I wanted him to actually go inside the world of video games. So I thought it would be a good chance to make it a new IP of its own, that's why it's not No More Heroes.